Compound Enzyme‐Assisted Extraction and Characterization of <i>Trigonella foenum‐graecum</i> L. Polysaccharides and Their Ameliorative Effects on MAFLD
, under which the polysaccharide yield reached 24.88% ± 0.15%. The molecular weight distribution of fenugreek seed polysaccharides was 7157.46, 2785.65, and 642.61 Da, and they were mainly composed of mannose and galactose. In vivo experiments indicated that DFSP exerted a liver-protective effect on MAFLD mice, accompanied by improvements in lipid metabolic parameters, antioxidant capacity, and inflammatory responses. Therefore, this study provides a scientific basis for further investigations into the fine structure and potential hepatoprotective effects of DFSP.
Authors
- Guoqiang Li (ORCID: https://orcid.org/0000-0003-3223-4007)
- Cun‐Ping Wang
- Hong‐Tao Bi
- Wen‐Xuan Zhao
- Yan‐Feng He
- Rui Zhang
Institutions
- Qinghai University (CN)
- Qinghai Tibetan Hospital (CN)
- Institute of Tibetan Plateau Research (CN)
- Qinghai Provincial Peoples Hospital (CN)
Publication Details
- Journal
- Chemistry & Biodiversity
- Published
- 2026-05-01
- DOI
- https://doi.org/10.1002/cbdv.202503580
- Primary Topic
- Natural Antidiabetic Agents Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00