Compound Enzyme‐Assisted Extraction and Characterization of <i>Trigonella foenum‐graecum</i> L. Polysaccharides and Their Ameliorative Effects on MAFLD

, under which the polysaccharide yield reached 24.88% ± 0.15%. The molecular weight distribution of fenugreek seed polysaccharides was 7157.46, 2785.65, and 642.61 Da, and they were mainly composed of mannose and galactose. In vivo experiments indicated that DFSP exerted a liver-protective effect on MAFLD mice, accompanied by improvements in lipid metabolic parameters, antioxidant capacity, and inflammatory responses. Therefore, this study provides a scientific basis for further investigations into the fine structure and potential hepatoprotective effects of DFSP.

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Publication Details

Journal
Chemistry & Biodiversity
Published
2026-05-01
DOI
https://doi.org/10.1002/cbdv.202503580
Primary Topic
Natural Antidiabetic Agents Studies
Type
article
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article

Compound Enzyme‐Assisted Extraction and Characterization of Trigonella foenum‐graecum L. Polysaccharides and Their Ameliorative Effects on MAFLD

Guoqiang Li, Cun‐Ping Wang, Hong‐Tao Bi, Wen‐Xuan Zhao et al.
Chemistry & Biodiversity
Natural Antidiabetic Agents Studies
article

Compound Enzyme‐Assisted Extraction and Characterization of Trigonella foenum‐graecum L. Polysaccharides and Their Ameliorative Effects on MAFLD

Guoqiang Li, Cun‐Ping Wang, Hong‐Tao Bi, Wen‐Xuan Zhao, Yan‐Feng He, Rui Zhang
article en

Abstract

, under which the polysaccharide yield reached 24.88% ± 0.15%. The molecular weight distribution of fenugreek seed polysaccharides was 7157.46, 2785.65, and 642.61 Da, and they were mainly composed of mannose and galactose. In vivo experiments indicated that DFSP exerted a liver-protective effect on MAFLD mice, accompanied by improvements in lipid metabolic parameters, antioxidant capacity, and inflammatory responses. Therefore, this study provides a scientific basis for further investigations into the fine structure and potential hepatoprotective effects of DFSP.

Chemistry & BiodiversityVol. 23(5)
Qinghai University (CN), Qinghai Tibetan Hospital (CN), Institute of Tibetan Plateau Research (CN), Qinghai Provincial Peoples Hospital (CN)
Clean water and sanitation
Openalex Percentile: Top 7%
Natural Antidiabetic Agents Studies
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Compound Enzyme‐Assisted Extraction and Characterization of <i>Trigonella foenum‐graecum</i> L. Polysaccharides and Their Ameliorative Effects on MAFLD — Guoqiang Li, Cun‐Ping Wang, et al. · Chemistry & Biodiversity (2026) | TGRS Research Map | TGRS