Reprogramming T cell-myeloid crosstalk overcomes immune resistance in colorectal cancer
T cells, while reducing immunosuppressive myeloid infiltration and T cell exhaustion, identifying key cellular programs that overcome immune escape in CRC.
Authors
- Nam Woo Cho (ORCID: https://orcid.org/0000-0002-5785-9698)
- Natalie Vaninov (ORCID: https://orcid.org/0000-0002-5133-6941)
- Nicolas Vabret (ORCID: https://orcid.org/0000-0002-0846-1819)
- Robert Samstein (ORCID: https://orcid.org/0000-0001-6860-2401)
- Aparna Ananthanarayanan (ORCID: https://orcid.org/0000-0003-4776-9952)
- Guillaume Mestrallet (ORCID: https://orcid.org/0000-0002-9514-313X)
- Cansu Cimen Bozkus
- Matthew Brown
- Leandra Velazquez
- Matthew Spitzer
- Nina Bhardwaj
Institutions
- University of California, San Francisco (US)
- Tisch Hospital (US)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- Cell Reports Medicine
- Published
- 2026-05-01
- DOI
- https://doi.org/10.1016/j.xcrm.2026.102786
- Primary Topic
- CAR-T cell therapy research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health