CHILD Syndrome without Limb Defects in a 1-year-old: revised nomenclature and successful treatment with Topical 2% Simvastatin/2% Cholesterol
The recent publication of a new gene-based classification for the ichthyoses has drawn attention to naming anomalies in other conditions. An example is CHILD syndrome (Congenital Ichthyosiform Erythroderma with Limb Defects) without Limb Defects, as reported here. We suggest nomenclature in line with the system used for the ichthyoses. We also report successful pathogenesis-based treatment in a very young child.
Authors
- Samantha Ibbs
- Pratima Poudel (ORCID: https://orcid.org/0000-0001-5725-187X)
- Joseph Wyer (ORCID: https://orcid.org/0009-0006-7861-4207)
- Celia Moss (ORCID: https://orcid.org/0000-0003-1773-4011)
Institutions
- Birmingham Women's Hospital (GB)
- Birmingham Children's Hospital (GB)
- Birmingham Women’s and Children’s NHS Foundation Trust (GB)
- University of Birmingham (GB)
Publication Details
- Journal
- Clinical and Experimental Dermatology
- Published
- 2026-05-01
- DOI
- https://doi.org/10.1093/ced/llag193
- Primary Topic
- Genetic and rare skin diseases.
- Type
- article
- Field-Weighted Citation Impact
- 0.00