Microalgal protein–alginate cryogels for enhanced lyoprotection, gastrointestinal stability, and controlled release of Lacticaseibacillus rhamnosus GG
), showing a strong correlation with post-digestion viability. Overall, microalgal proteins, particularly SPI, govern the interplay between cryogel structure, physical state, and colloidal behaviour. This allows for high lyoprotection, prolonged shelf-life, and improved gastrointestinal survivability and cell adhesion properties, matching or exceeding those of conventional lyophilised microcarriers.
Authors
- Claire Gaïani (ORCID: https://orcid.org/0000-0003-0434-8453)
- Jennyfer Fortuin (ORCID: https://orcid.org/0000-0002-5998-4820)
- Sébastien Cambier (ORCID: https://orcid.org/0000-0001-7761-5212)
- Servane Contal
- Vincenzo Fogliano (ORCID: https://orcid.org/0000-0001-8786-9355)
- Frédéric Addiego (ORCID: https://orcid.org/0000-0002-4081-9526)
- Christos Soukoulis (ORCID: https://orcid.org/0000-0003-2288-0910)
- Benoît Marcolini (ORCID: https://orcid.org/0009-0009-2263-2619)
- Marcus Iken
- Jerome Bour
Institutions
- Luxembourg Institute of Science and Technology (LU)
- INTRASOFT International (Luxembourg) (LU)
- Laboratoire d'Ingénierie des Biomolécules
- Université de Lorraine (FR)
- Wageningen University & Research (NL)
Publication Details
- Journal
- Journal of Controlled Release
- Published
- 2026-05-01
- DOI
- https://doi.org/10.1016/j.jconrel.2026.114989
- Primary Topic
- Seaweed-derived Bioactive Compounds
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Fonds National de la Recherche Luxembourg