Characterizing morphological variations of feathery cataract using AS-OCT in post-vitrectomy eyes

OBJECTIVE: To characterize the morphological variations of feathery cataracts observed in post-vitrectomy gas-filled eyes using anterior segment optical coherence tomography (AS-OCT). METHODS: A prospective observational study with a total of 25 eyes with transient feathery cataracts following gas-filled vitrectomy was included for AS-OCT evaluation of the posterior lens and capsule. Imaging was performed on postoperative day 1 and day 7 for all cases. The morphological variations of feathery cataracts were characterized using AS-OCT. RESULTS: Three distinct morphological patterns were identified based on the appearance of vacuoles on AS-OCT: dome-shaped, cuboidal-shaped, and diffuse thickening with poorly defined cystic spaces. Complete resolution of AS-OCT-defined morphological patterns was observed in all eyes within 7-10 days. CONCLUSIONS: The morphological characterization of feathery cataracts using AS-OCT is a novel finding and has not been previously reported. This novel imaging-based classification can aid in refining postoperative monitoring protocols and contribute to a better understanding of cataractogenesis mechanisms in gas-filled eyes.