Case report: A rare case of retroperitoneal mixed type unicentric Castleman disease

Objective To enhance the understanding, diagnosis, and management of retroperitoneal mixed type unicentric Castleman disease. Methods This report describes a case of retroperitoneal mixed type unicentric Castleman disease managed at our institution. The clinical presentation, histopathological characteristics, and therapeutic approach are detailed. A discussion regarding the current status of diagnosis, management, and prognosis is provided, supplemented by a review of the relevant literature. Results A 52-year-old female was admitted with a chief complaint of “frequent urination for over 6 months.” A retroperitoneal mass was identified. The patient underwent laparoscopic excision of the retroperitoneal mass. Postoperative pathological examination confirmed the diagnosis of mixed type unicentric Castleman disease. The patient’s postoperative recovery was uneventful, and she remains under close follow-up surveillance. Conclusion Retroperitoneal mixed type unicentric Castleman disease is clinically uncommon and possesses distinctive histopathological features. Awareness of this entity needs to be heightened.