Development of Plant-derived Extracellular Vesicle-based Therapeutic Systems

, a clinically used liposomal formulation of doxorubicin, inducing apoptosis in colon26 cells and suppressing peritoneal dissemination in vivo. These findings highlight the potential of rbNPs as sustainable nanomedicines with therapeutic activity and environmental value. In conclusion, pdNPs, particularly cNPs and rbNPs, are cost-effective, safe, and sustainable biomaterials with great potential for advancing cancer therapy, vaccine development, and drug delivery systems.

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Publication Details

Journal
YAKUGAKU ZASSHI
Published
2026-04-30
DOI
https://doi.org/10.1248/yakushi.25-00171-3
Primary Topic
Extracellular vesicles in disease
Type
article
Field-Weighted Citation Impact
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article

Development of Plant-derived Extracellular Vesicle-based Therapeutic Systems

Kosuke Kusamori, Shoko Itakura, Makiya Nishikawa
YAKUGAKU ZASSHI
Extracellular vesicles in disease
article

Development of Plant-derived Extracellular Vesicle-based Therapeutic Systems

Kosuke Kusamori, Shoko Itakura, Makiya Nishikawa
article en

Abstract

, a clinically used liposomal formulation of doxorubicin, inducing apoptosis in colon26 cells and suppressing peritoneal dissemination in vivo. These findings highlight the potential of rbNPs as sustainable nanomedicines with therapeutic activity and environmental value. In conclusion, pdNPs, particularly cNPs and rbNPs, are cost-effective, safe, and sustainable biomaterials with great potential for advancing cancer therapy, vaccine development, and drug delivery systems.

YAKUGAKU ZASSHIVol. 146(5)
Tokyo University of Science (JP)
Openalex Percentile: Top 10%
Extracellular vesicles in disease
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