Green Chemistry Strategies in the Development of Sustainable Multi-Nutrient Fertilizers for Enhanced Soil and Crop Health

The growing demand for food production has increased the pressure on soil and fertilizer use, often leading to nutrient losses, soil degradation, and environmental pollution. Green chemistry offers practical solutions to these challenges by encouraging cleaner, safer, and more efficient ways of producing and using fertilizers. This review summarizes recent advances in multi-nutrient sustainable fertilizers developed through green chemistry principles, including renewable raw materials, low-toxicity synthesis methods, and environmentally friendly delivery systems. Different approaches, such as controlled-release carriers, nano-enabled formulations, chelated nutrients, and bio-based coatings, are discussed with a focus on how they reduce nutrient losses and improve soil and plant health. The review also highlights the benefits and limitations of these technologies, gaps in current research, and the need for long-term field studies to assess their safety and effectiveness. Overall, green chemistry-guided fertilizer development shows strong potential to support sustainable agriculture by improving nutrient efficiency while reducing environmental impacts.