Pseudomeningocele-Related Hydrocephalus After Spinal Tumor Resection: Case Report and Systematic Review of Pathophysiology and Treatment Options

Pseudomeningocele-related hydrocephalus after spinal tumor resection is a rare condition. Only few cases are reported and the pathophysiology of this condition is still debated in literature. This article presents the case of a 44-years-old woman that developed cervical pseudomeningocele and hydrocephalus after the resection of a C2 schwannoma. After different surgeries, the resolution of the pseudomeningocele has resolved the hydrocephalus. Some authors yet suggested that the surgical management of the cerebro-spinal fluid (CSF) leak can also resolve the hydrocephalus. Several theories about the pathophysiological correlation between these two conditions and their treatment have been proposed. This illustrative case offers the possibility to better evaluate this association and a new theory is proposed.

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Journal
World Neurosurgery
Published
2026-05-01
DOI
https://doi.org/10.1016/j.wneu.2026.125021
Primary Topic
Spinal Dysraphism and Malformations
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article
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article

Pseudomeningocele-Related Hydrocephalus After Spinal Tumor Resection: Case Report and Systematic Review of Pathophysiology and Treatment Options

Flavio Panico, Alessandro Fiumefreddo, Nicola Pio Fochi, Filippo Lacatena et al.
World Neurosurgery
Spinal Dysraphism and Malformations
article

Pseudomeningocele-Related Hydrocephalus After Spinal Tumor Resection: Case Report and Systematic Review of Pathophysiology and Treatment Options

Flavio Panico, Alessandro Fiumefreddo, Nicola Pio Fochi, Filippo Lacatena, Stefano Colonna, Diego Garbossa, Fabio Cofano, Alberto Morello, Enrico Lo Bue
article en

Abstract

Pseudomeningocele-related hydrocephalus after spinal tumor resection is a rare condition. Only few cases are reported and the pathophysiology of this condition is still debated in literature. This article presents the case of a 44-years-old woman that developed cervical pseudomeningocele and hydrocephalus after the resection of a C2 schwannoma. After different surgeries, the resolution of the pseudomeningocele has resolved the hydrocephalus. Some authors yet suggested that the surgical management of the cerebro-spinal fluid (CSF) leak can also resolve the hydrocephalus. Several theories about the pathophysiological correlation between these two conditions and their treatment have been proposed. This illustrative case offers the possibility to better evaluate this association and a new theory is proposed.

World Neurosurgery
University of Turin (IT)
Good health and well-being
Openalex Percentile: Top 9%
Spinal Dysraphism and Malformations
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Pseudomeningocele-Related Hydrocephalus After Spinal Tumor Resection: Case Report and Systematic Review of Pathophysiology and Treatment Options — Flavio Panico, Alessandro Fiumefreddo, et al. · World Neurosurgery (2026) | TGRS Research Map | TGRS