Abdominal Obesity Phenotypes and Incidence of Type 2 DM, Cardiovascular Outcomes and All‐Cause Mortality—A Systematic Review and Meta‐Analysis
Background and Aims: The global rise in obesity, a major driver of metabolic diseases, has prompted scrutiny of distinct obesity phenotypes. While overall obesity is concerning, abdominal obesity demonstrates a stronger association with metabolic dysfunction, type 2 diabetes (DM2), and cardiovascular disease (CVD). This review examines the risk of DM2, CVD, and mortality in adults with a metabolically healthy abdominal obese phenotype. Methods: ² statistic. Results: ² > 50%) was observed, partly explained by differences in outcome definitions and metabolic classifications. Conclusion: PROSPERO (CRD42019111056).
Authors
- Marjan Momeni (ORCID: https://orcid.org/0000-0003-2551-4895)
- Azam Doustmohammadian (ORCID: https://orcid.org/0000-0001-6249-2520)
- Soraya Doustmohamadian (ORCID: https://orcid.org/0000-0001-8642-1970)
- Farhad Hosseinpanah (ORCID: https://orcid.org/0000-0001-5235-9451)
- Majid Mirmohammadkhani
Institutions
- Iran University of Medical Sciences (IR)
- Research Institute for Endocrine Sciences (IR)
- Semnan University of Medical Sciences (IR)
- Shahid Beheshti University of Medical Sciences (IR)
Publication Details
- Journal
- Health Science Reports
- Published
- 2026-05-01
- DOI
- https://doi.org/10.1002/hsr2.72028
- Primary Topic
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Type
- article
- Field-Weighted Citation Impact
- 0.00