Abdominal Obesity Phenotypes and Incidence of Type 2 DM, Cardiovascular Outcomes and All‐Cause Mortality—A Systematic Review and Meta‐Analysis

Background and Aims: The global rise in obesity, a major driver of metabolic diseases, has prompted scrutiny of distinct obesity phenotypes. While overall obesity is concerning, abdominal obesity demonstrates a stronger association with metabolic dysfunction, type 2 diabetes (DM2), and cardiovascular disease (CVD). This review examines the risk of DM2, CVD, and mortality in adults with a metabolically healthy abdominal obese phenotype. Methods: ² statistic. Results: ² > 50%) was observed, partly explained by differences in outcome definitions and metabolic classifications. Conclusion: PROSPERO (CRD42019111056).

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Journal
Health Science Reports
Published
2026-05-01
DOI
https://doi.org/10.1002/hsr2.72028
Primary Topic
Diabetes, Cardiovascular Risks, and Lipoproteins
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article
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article

Abdominal Obesity Phenotypes and Incidence of Type 2 DM, Cardiovascular Outcomes and All‐Cause Mortality—A Systematic Review and Meta‐Analysis

Marjan Momeni, Azam Doustmohammadian, Soraya Doustmohamadian, Farhad Hosseinpanah et al.
Health Science Reports
Diabetes, Cardiovascular Risks, and Lipoproteins
article

Abdominal Obesity Phenotypes and Incidence of Type 2 DM, Cardiovascular Outcomes and All‐Cause Mortality—A Systematic Review and Meta‐Analysis

Marjan Momeni, Azam Doustmohammadian, Soraya Doustmohamadian, Farhad Hosseinpanah, Majid Mirmohammadkhani
article en

Abstract

Background and Aims: The global rise in obesity, a major driver of metabolic diseases, has prompted scrutiny of distinct obesity phenotypes. While overall obesity is concerning, abdominal obesity demonstrates a stronger association with metabolic dysfunction, type 2 diabetes (DM2), and cardiovascular disease (CVD). This review examines the risk of DM2, CVD, and mortality in adults with a metabolically healthy abdominal obese phenotype. Methods: ² statistic. Results: ² > 50%) was observed, partly explained by differences in outcome definitions and metabolic classifications. Conclusion: PROSPERO (CRD42019111056).

Health Science ReportsVol. 9(5)
Iran University of Medical Sciences (IR), Research Institute for Endocrine Sciences (IR), Semnan University of Medical Sciences (IR), Shahid Beheshti University of Medical Sciences (IR)
Good health and well-being
Openalex Percentile: Top 9%
Diabetes, Cardiovascular Risks, and Lipoproteins
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Abdominal Obesity Phenotypes and Incidence of Type 2 DM, Cardiovascular Outcomes and All‐Cause Mortality—A Systematic Review and Meta‐Analysis — Marjan Momeni, Azam Doustmohammadian, et al. · Health Science Reports (2026) | TGRS Research Map | TGRS