Medical Technology and Life Expectancy: Evidence from the Antitoxin Treatment of Diphtheria

We examine the impact of the free supply of diphtheria antitoxin, the first effective medical treatment for an infectious disease, on the historical health transition in Massachusetts. Using newly collected municipality-level data on the distribution of antitoxin and information from over 1.5 million death certificates from 1880 to 1914, we find that the rapid availability of antitoxin treatment significantly increased life expectancy at young ages. Our findings suggest that medicine, combined with an effective public health policy, played a more important role in improving life expectancy in the early twentieth century than previously thought. (JEL H75, I12, I18, J13, N31)

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Publication Details

Journal
American Economic Journal Economic Policy
Published
2026-04-29
DOI
https://doi.org/10.1257/pol.20240087
Primary Topic
Historical Economic and Social Studies
Type
article
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0.00
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article

Medical Technology and Life Expectancy: Evidence from the Antitoxin Treatment of Diphtheria

Peter Z. Lin, C Pilebaek Hansen, Philipp Ager
American Economic Journal Economic Policy
Historical Economic and Social Studies
article

Medical Technology and Life Expectancy: Evidence from the Antitoxin Treatment of Diphtheria

Peter Z. Lin, C Pilebaek Hansen, Philipp Ager
article en

Abstract

We examine the impact of the free supply of diphtheria antitoxin, the first effective medical treatment for an infectious disease, on the historical health transition in Massachusetts. Using newly collected municipality-level data on the distribution of antitoxin and information from over 1.5 million death certificates from 1880 to 1914, we find that the rapid availability of antitoxin treatment significantly increased life expectancy at young ages. Our findings suggest that medicine, combined with an effective public health policy, played a more important role in improving life expectancy in the early twentieth century than previously thought. (JEL H75, I12, I18, J13, N31)

American Economic Journal Economic PolicyVol. 18(2)
University of Copenhagen (DK), Center for Economic and Policy Research (US), University of Mannheim (DE), Western Kentucky University (US)
Openalex Percentile: Top 5%
Historical Economic and Social Studies
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Medical Technology and Life Expectancy: Evidence from the Antitoxin Treatment of Diphtheria — Peter Z. Lin, C Pilebaek Hansen, et al. · American Economic Journal Economic Policy (2026) | TGRS Research Map | TGRS