Biotransformation of progesterone by Aspergillus welwitschiae CCMB 674 yields a novel metabolite 11α,21-dihydroxyprogesterone, alongside three known compounds
after 168 h. These findings highlight A. welwitschiae as a promising biocatalyst for selective steroid hydroxylation.
Authors
- Diogo Montes Vidal (ORCID: https://orcid.org/0000-0002-1157-4179)
- Ribeiro de Oliveira (ORCID: https://orcid.org/0000-0002-7015-4350)
- Rodrigo Maia de Pádua (ORCID: https://orcid.org/0000-0002-9939-6900)
- Lucas Penha Dutra (ORCID: https://orcid.org/0000-0003-3119-0807)
- Lucienir Pains Duarte (ORCID: https://orcid.org/0000-0002-8885-6625)
- Marcos Luiz Dias de Souza
- Aristóteles Góes-Neto
Institutions
- Universidade Federal de Minas Gerais (BR)
- Universidade Federal do Paraná (BR)
Publication Details
- Journal
- Steroids
- Published
- 2026-05-01
- DOI
- https://doi.org/10.1016/j.steroids.2026.109792
- Primary Topic
- Steroid Chemistry and Biochemistry
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- Fundação de Amparo à Pesquisa do Estado de Minas Gerais