Comparative efficacy of different mind–body exercises on functional capacity and quality of life in patients with chronic heart failure: a systematic review and network meta-analysis

Background and objective Mind–body exercise (MBE) has emerged as a vital adjunctive modality in the rehabilitation of chronic heart failure (CHF). However, the relative advantages of various MBE types in improving functional capacity and quality of life (QoL) remain elusively defined. This study aimed to compare the therapeutic efficacy of different MBEs on clinical outcomes in CHF patients using a network meta-analysis (NMA). Methods A systematic search was conducted across databases including PubMed, Embase, Web of Science, and the Cochrane Library for randomized controlled trials (RCTs) investigating MBE interventions in CHF, spanning from database inception to January 12, 2026. Two researchers independently performed literature screening, data extraction, and risk of bias assessment (RoB 2.0). R software was utilized for network meta-analysis, SUCRA (Surface Under the Cumulative Ranking Curve) ranking, cluster analysis, and Egger’s test for publication bias. The certainty of evidence was evaluated using the CINeMA (Confidence in Network Meta-Analysis) framework. Results Twenty-eight RCTs were ultimately included. The NMA results indicated that Yijinjing was significantly superior to conventional care in improving quality of life (MLHFQ), cardiopulmonary endurance (Peak VO 2 ), and cardiac systolic function (LVEF), as well as in reducing cardiac load indicators (NT-proBNP). Furthermore, Yijinjing yielded the highest SUCRA values (0.858–1.000) across these outcomes, demonstrating a high potential intervention probability. Regarding the enhancement of exercise tolerance (6MWD), Meditation showed the highest potential probability (SUCRA = 0.675); however, pairwise comparisons revealed no statistically significant differences between any MBE and conventional care ( p > 0.05). Cluster analysis further confirmed a synergistic trend of Yijinjing, Liuzijue, and Meditation in enhancing both QoL and exercise endurance. No significant publication bias was detected by Egger’s test for any outcome ( p > 0.05). The certainty of evidence based on CINeMA was rated as Moderate. Conclusion Based on moderate-certainty evidence, Yijinjing shows the highest potential probability for promoting cardiac functional recovery and enhancing quality of life in CHF patients, while meditation particularly of the movement-integrated type shows potential advantages in strengthening functional exercise tolerance. Given the lack of statistical significance in certain indicators (e.g., 6MWD), future intervention designs should focus on the regulatory effects of mind–body integration on kinesiophobia to develop more precise and long-term validated rehabilitation strategies. Systematic review registration www.crd.york.ac.uk/prospero , CRD420261308623.

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Journal
Frontiers in Public Health
Published
2026-05-01
DOI
https://doi.org/10.3389/fpubh.2026.1802127
Primary Topic
Cardiovascular and exercise physiology
Type
article
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article

Comparative efficacy of different mind–body exercises on functional capacity and quality of life in patients with chronic heart failure: a systematic review and network meta-analysis

Bin Gai, Jiayi Yao, Shiguan Jia, Yongliang Zhu et al.
Frontiers in Public Health
Cardiovascular and exercise physiology
article

Comparative efficacy of different mind–body exercises on functional capacity and quality of life in patients with chronic heart failure: a systematic review and network meta-analysis

Bin Gai, Jiayi Yao, Shiguan Jia, Yongliang Zhu, Haozhe Wang, Junhao He, Peng Suo
article en

Abstract

Background and objective Mind–body exercise (MBE) has emerged as a vital adjunctive modality in the rehabilitation of chronic heart failure (CHF). However, the relative advantages of various MBE types in improving functional capacity and quality of life (QoL) remain elusively defined. This study aimed to compare the therapeutic efficacy of different MBEs on clinical outcomes in CHF patients using a network meta-analysis (NMA). Methods A systematic search was conducted across databases including PubMed, Embase, Web of Science, and the Cochrane Library for randomized controlled trials (RCTs) investigating MBE interventions in CHF, spanning from database inception to January 12, 2026. Two researchers independently performed literature screening, data extraction, and risk of bias assessment (RoB 2.0). R software was utilized for network meta-analysis, SUCRA (Surface Under the Cumulative Ranking Curve) ranking, cluster analysis, and Egger’s test for publication bias. The certainty of evidence was evaluated using the CINeMA (Confidence in Network Meta-Analysis) framework. Results Twenty-eight RCTs were ultimately included. The NMA results indicated that Yijinjing was significantly superior to conventional care in improving quality of life (MLHFQ), cardiopulmonary endurance (Peak VO 2 ), and cardiac systolic function (LVEF), as well as in reducing cardiac load indicators (NT-proBNP). Furthermore, Yijinjing yielded the highest SUCRA values (0.858–1.000) across these outcomes, demonstrating a high potential intervention probability. Regarding the enhancement of exercise tolerance (6MWD), Meditation showed the highest potential probability (SUCRA = 0.675); however, pairwise comparisons revealed no statistically significant differences between any MBE and conventional care ( p > 0.05). Cluster analysis further confirmed a synergistic trend of Yijinjing, Liuzijue, and Meditation in enhancing both QoL and exercise endurance. No significant publication bias was detected by Egger’s test for any outcome ( p > 0.05). The certainty of evidence based on CINeMA was rated as Moderate. Conclusion Based on moderate-certainty evidence, Yijinjing shows the highest potential probability for promoting cardiac functional recovery and enhancing quality of life in CHF patients, while meditation particularly of the movement-integrated type shows potential advantages in strengthening functional exercise tolerance. Given the lack of statistical significance in certain indicators (e.g., 6MWD), future intervention designs should focus on the regulatory effects of mind–body integration on kinesiophobia to develop more precise and long-term validated rehabilitation strategies. Systematic review registration www.crd.york.ac.uk/prospero , CRD420261308623.

Frontiers in Public HealthVol. 14
China University of Mining and Technology (CN), Shandong Sport University (CN), Capital University of Physical Education and Sports (CN)
Openalex Percentile: Top 5%
Cardiovascular and exercise physiology
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