Transcatheter Folded Valve Placement Within a Patent Ductus Arteriosus for Pulmonary Hypertension
BACKGROUND: Severe pulmonary arterial hypertension (PAH) with bidirectional patent ductus arteriosus (PDA) presents a challenge, as ductal closure is contraindicated. CASE SUMMARY: A 14-year-old boy with severe PAH and bidirectional PDA experienced exercise intolerance. He underwent transcatheter placement of a 20-mm folded Melody valve within the native PDA. The procedure eliminated diastolic left-to-right shunting while preserving systolic right-to-left shunting. At 1-year follow-up, he demonstrated durable unidirectional shunting and improved to NYHA functional class I status. DISCUSSION: While surgical valved reverse Potts shunts exist in the literature, adapting a transcatheter valve to create a unidirectional shunt within the native PDA percutaneously is novel. It offers a less invasive alternative for managing suprasystemic PAH. TAKE-HOME MESSAGES: Transcatheter folded valve placement within a native PDA safely establishes a unidirectional right-to-left shunt. This intervention reduces pulmonary overcirculation while maintaining vital ventricular decompression.
Authors
- Eli S. Fredman (ORCID: https://orcid.org/0009-0005-8847-8758)
- Hadeel Allam (ORCID: https://orcid.org/0009-0004-0677-0089)
- Nidhy P. Varghese
- R. Mark Grady
- Manish Aggarwal
- Daisuke Kobayashi
- David Balzer
Institutions
- St. Louis Children's Hospital (US)
- Texas Children's Hospital (US)
Publication Details
- Journal
- JACC Case Reports
- Published
- 2026-05-01
- DOI
- https://doi.org/10.1016/j.jaccas.2026.108137
- Primary Topic
- Cardiovascular Conditions and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00