Emerging Cost‐Effective Manufacturing Technologies for Advanced Biomedical Devices

ABSTRACT Conventional medical device manufacturing is hindered by high costs, lengthy production cycles, and dependence on specialized infrastructure, while clinical needs increasingly prioritize personalization, functional integration, and accessibility. To address this gap and clarify the field, this review systematically summarizes key advances in low‐cost fabrication technologies, including 3D printing and laser processing. It further explores functional materials and devices inspired by everyday items such as LEGO blocks and origami, alongside metamaterials with a negative Poisson's ratio and diverse bioinspired architectures mimicking natural structures. Artificial intelligence also plays a critical supporting role in structural design, driving cost reduction, improved efficiency, and intelligent manufacturing. By integrating fabrication strategies, structural innovation, intelligent algorithms, and real‐world applications, this work reveals mechanisms for cost control and performance improvement, directly advancing low‐cost, high‐performance, multifunctional biomedical devices. It offers valuable guidance for clinical translation and industrial upgrading of next‐generation affordable medical technologies.

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Publication Details

Journal
Advanced Materials Technologies
Published
2026-05-01
DOI
https://doi.org/10.1002/admt.71017
Primary Topic
3D Printing in Biomedical Research
Type
article
Field-Weighted Citation Impact
0.00

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article

Emerging Cost‐Effective Manufacturing Technologies for Advanced Biomedical Devices

Bingbing Gao, Tong Wu, Yuchen Pan, X Q Li
Advanced Materials Technologies
3D Printing in Biomedical Research
article

Emerging Cost‐Effective Manufacturing Technologies for Advanced Biomedical Devices

Bingbing Gao, Tong Wu, Yuchen Pan, X Q Li
article en

Abstract

ABSTRACT Conventional medical device manufacturing is hindered by high costs, lengthy production cycles, and dependence on specialized infrastructure, while clinical needs increasingly prioritize personalization, functional integration, and accessibility. To address this gap and clarify the field, this review systematically summarizes key advances in low‐cost fabrication technologies, including 3D printing and laser processing. It further explores functional materials and devices inspired by everyday items such as LEGO blocks and origami, alongside metamaterials with a negative Poisson's ratio and diverse bioinspired architectures mimicking natural structures. Artificial intelligence also plays a critical supporting role in structural design, driving cost reduction, improved efficiency, and intelligent manufacturing. By integrating fabrication strategies, structural innovation, intelligent algorithms, and real‐world applications, this work reveals mechanisms for cost control and performance improvement, directly advancing low‐cost, high‐performance, multifunctional biomedical devices. It offers valuable guidance for clinical translation and industrial upgrading of next‐generation affordable medical technologies.

Advanced Materials Technologies
China Pharmaceutical University (CN)
National Natural Science Foundation of China, National Key Research and Development Program of China
Industry, innovation and infrastructure
Openalex Percentile: Top 11%
3D Printing in Biomedical Research
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