Good surgical practice

Good surgical practice Good surgical practice (GSP) is essential in pre-clinical research. In line with the principles of Replacement, Reduction, and Refinement (3Rs), we are ethically and legally committed to safeguarding the well-being of laboratory animals. This paper will focus on the history of GSP, which began in the late 1800s, when, thanks to the discovery of ether as an an-aesthetic, modern surgery was established.