Longitudinal Study of Plasma NFL and GFAP as Biomarkers of Alcohol Withdrawal–Associated Brain Injury
). This longitudinal study provided preliminary indication that brain injury could occur within the first days of AW, especially in patients with severe pharmacological dependence. Plasma NFL and GFAP are promising biomarkers of AW-related brain pathology and should be investigated as biomarkers of therapeutic response to test innovative drug strategies for preventing this toxicity. Trial Registration: Clinical Trials: NCT05216705.
Authors
- Frank Bellivier (ORCID: https://orcid.org/0000-0002-3660-6640)
- Dorian Rollet (ORCID: https://orcid.org/0000-0003-0442-5236)
- Élodie Bouaziz-Amar (ORCID: https://orcid.org/0000-0003-0880-5826)
- Jérôme Jeanblanc (ORCID: https://orcid.org/0000-0003-0353-2777)
- Vanessa Bloch (ORCID: https://orcid.org/0000-0002-2582-6349)
- Alexandra Dereux (ORCID: https://orcid.org/0000-0003-1292-2793)
- Claire Paquet (ORCID: https://orcid.org/0000-0002-2273-7316)
- Frank Questel
- Cynthia Marie‐Claire (ORCID: https://orcid.org/0000-0002-2282-134X)
- Florence Vorspan (ORCID: https://orcid.org/0000-0001-5168-3727)
- Romain Icick (ORCID: https://orcid.org/0000-0002-5078-4048)
- Julien Azuar (ORCID: https://orcid.org/0000-0002-7732-2265)
- Virgile Clergue‐Duval (ORCID: https://orcid.org/0000-0003-2803-8249)
- Jean‐Louis Laplanche
- Mickael Naassila (ORCID: https://orcid.org/0000-0002-9788-0918)
Institutions
- Inserm (FR)
- Université Paris Cité (FR)
- International Network for Economic, Social and Cultural Rights (US)
- Sorbonne Paris Cité (FR)
- Assistance Publique – Hôpitaux de Paris (FR)
- Groupe de Recherche sur l'Alcool et les Pharmacodépendances (FR)
- Hôpital Fernand-Widal (FR)
- Hôpital Lariboisière (FR)
- Laboratoire d'Optique Appliquée (FR)
- Amer Sports (France) (FR)
- FHU Neurovasc (FR)
- Université de Picardie Jules Verne (FR)
Publication Details
- Journal
- Addiction Biology
- Published
- 2026-05-01
- DOI
- https://doi.org/10.1111/adb.70157
- Primary Topic
- Alcoholism and Thiamine Deficiency
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Institut National de la Santé et de la Recherche Médicale