Evaluating the Impact of Female Factors on Specific Stages of Early Embryo Development: A Retrospective Analysis of 1372 IVF Cycles

Purpose: To ascertain whether female factors uniformly impact the entire spectrum of early embryo development during in vitro fertilization (IVF) treatments or if their influence is confined to specific stages. Methods: A retrospective observational study. Univariate and multivariate logistic regression analyses were performed to identify the influence of female factors on different stages of embryo development. Results: <0.05). Conclusion: Female factors exert stage-specific effects on early embryo development in IVF, supporting the need for individualized clinical strategies. Notably, an optimal LH/FSH ratio was associated with improved blastocyst quality, although prospective studies are warranted to validate this threshold and its clinical applicability.