Network meta‐analysis finds dexmedetomidine broadly effective for postoperative delirium

The selective alpha‐2 adrenergic agonist dexmedetomidine showed the most broadly effective results in preventing postoperative delirium in older adults in a systematic review and meta‐analysis comprising 18 randomized trials. Corticosteroids were the only treatments found to reduce delirium severity.

Publication Details

Journal
The Brown University Psychopharmacology Update
Published
2026-04-30
DOI
https://doi.org/10.1002/pu.31452
Primary Topic
Intensive Care Unit Cognitive Disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Network meta‐analysis finds dexmedetomidine broadly effective for postoperative delirium

The Brown University Psychopharmacology Update
Intensive Care Unit Cognitive Disorders
article

Network meta‐analysis finds dexmedetomidine broadly effective for postoperative delirium

article en

Abstract

The selective alpha‐2 adrenergic agonist dexmedetomidine showed the most broadly effective results in preventing postoperative delirium in older adults in a systematic review and meta‐analysis comprising 18 randomized trials. Corticosteroids were the only treatments found to reduce delirium severity.

The Brown University Psychopharmacology UpdateVol. 37(6)
Openalex Percentile: Top 9%
Intensive Care Unit Cognitive Disorders
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Network meta‐analysis finds dexmedetomidine broadly effective for postoperative delirium · The Brown University Psychopharmacology Update (2026) | TGRS Research Map | TGRS