EVIDENCE-BASED AYURVEDA: BRIDGING ANCIENT WISDOM WITH MODERN SCIENTIFIC VALIDATION

Background: Ayurveda is one of the oldest systems of medicine, centered on maintaining health by balancing Doshas, Dhatus, and Agni (metabolic activity). In recent years, it has gained attention worldwide for its role in managing chronic diseases and promoting overall well-being. However, its wider acceptance in mainstream healthcare is still restricted due to limited high-quality scientific evidence. Objective: The present review attempts to examine the available scientific evidence on Ayurvedic medicines and therapies, identify existing challenges in research, and explore their relevance in the context of personalized healthcare. Methods: This narrative review is based on an analysis of published clinical studies, pharmacological research, and reports from recognized institutions. The focus was mainly on chronic conditions such as rheumatoid arthritis and metabolic disorders, along with commonly used classical formulations and therapeutic procedures. Results: A number of Ayurvedic formulations, including Chyawanprash, Arogyavardhini Vati, Ashwagandha, and Triphala, have shown encouraging results in terms of efficacy and safety. Similarly, therapies like Panchakarma, Kshara Sutra, Shirodhara, and leech therapy have demonstrated beneficial clinical outcomes. At the same time, several challenges remain, particularly due to the individualized nature of treatment, limitations of conventional trial methods, lack of measurable biomarkers, and concerns related to standardization. Conclusion: Ayurveda has the potential to contribute meaningfully to modern integrative healthcare. Strengthening research methodologies, improving standardization, and encouraging collaboration between traditional and modern sciences will be essential for its broader global acceptance.