Lanthanide(III) complexes of 4-aminoantipyrine Schiff base derivatives and their antimicrobial applications: A review

Lanthanides also known as lanthanoids (inner transition elements) constitute an interesting group of fifteen elements which are predominantly trivalent and exhibit similar physicochemical properties. These elements occupy the 4f inner transition series (lanthanides) in the periodic table. Over the years, the investigation of lanthanide(III) complexes has generated increased interest due to their interesting biological, photo-physical and magnetic properties. Lanthanide(III) complexes of Schiff bases of 4-aminontipyrine derivatives constitute another class of compounds that show remarkably interesting coordination and bio-inorganic chemistry. 4-Aminoantipyrine and its derivatives have formed stable complexes with many lanthanide metal ions. This literature review examines the lanthanide(III) complexes of 4-aminoantipyrine derivatives which were synthesized and characterized using various spectro-analytical techniques from which various structures were proposed. Antimicrobial applications of some of these lanthanide(III) complexes synthesized over the years were reported. This review serves as a guide for the development of new lanthanide(III) complexes of 4-aminoantipyrine derivatives as potential antibacterial and antifungal agents as well as other applications.