<i>Parvimonas micra</i> promotes carcinogenesis of colorectal cancer through phenyllactic acid‐induced DNA damage
mice. Aryl hydrocarbon receptor (AHR) inhibitor exhibited a therapeutic potential to reduce mice carcinogenesis. These findings established the role of P. micra and its metabolite, therefore providing diagnostic and therapeutic targets for treating CRC.
Authors
- Danling Liu (ORCID: https://orcid.org/0009-0007-9313-6378)
- Wanyi Zeng
- Jingbiao Zheng
- 尹锡棋
- Dayi Liang (ORCID: https://orcid.org/0009-0000-2679-9963)
- Mengze Xing (ORCID: https://orcid.org/0009-0005-9854-304X)
- Luo Z
- Wenhao Ma
- J I A H U I Wu
- Hongyu Xie
- Yanchun Xie
- Zhen He (ORCID: https://orcid.org/0000-0001-8735-6672)
- Shuang Guo
- Peng Lai
- Min Xia
- Mujia Cao
Institutions
- Sun Yat-sen University (CN)
- Sixth Affiliated Hospital of Sun Yat-sen University (CN)
Publication Details
- Journal
- Clinical and Translational Medicine
- Published
- 2026-05-01
- DOI
- https://doi.org/10.1002/ctm2.70667
- Primary Topic
- Carcinogens and Genotoxicity Assessment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- National Key Research and Development Program of China