Complete Low-Voltage Area Ablation in Persistent Atrial Fibrillation ― Post Hoc Subanalysis of the SUPPRESS-AF Trial ―
BACKGROUND: Incomplete low-voltage area (LVA) ablation may confound evaluation of its true efficacy in persistent atrial fibrillation (AF). This post hoc subanalysis of the multicenter randomized SUPPRESS-AF trial assessed the impact of complete LVA ablation. METHODS AND RESULTS: =0.099). CONCLUSIONS: Leaving LVA ablation incomplete to avoid complications appears reasonable. Although complete LVA ablation showed no overall superiority, LA enlargement may represent a clinically relevant factor for patient stratification.
Authors
- Tomoko Minamisaka
- Hirota Kida (ORCID: https://orcid.org/0000-0003-3718-554X)
- Nobuhiko Makino
- Yasuyuki Egami (ORCID: https://orcid.org/0000-0001-9728-6524)
- Shungo Hikoso (ORCID: https://orcid.org/0000-0003-2284-1970)
- Masaru Abe
- Y M Matsunaga-Lee
- the OCVC-SUPPRESS-AF investigators
- Naotaka Okamoto
- Hiroaki Nohara
- Akihiro Sunaga
- Yasuhiro Matsuda
- Tomoharu Dohi
- Koichi Inoue
- Koji Yasumoto
- Masato Okada
- Takafumi Oka
- Hitoshi Minamiguchi
- Masato Kawasaki
- Shodai Kawanami
- Masaharu Masuda
- Yasushi Sakata
- Koji Tanaka
- Yohei Sotomi
- Takashi Kanda
- Masami Nishino
- Masamichi Yano
- Tetsuya Watanabe
- Nobuaki K. Tanaka
Institutions
- Osaka Prefectural Medical Center (JP)
- Osaka National Hospital (JP)
- Osaka Rosai Hospital (JP)
- Kansai Rosai Hospital (JP)
- Nara Medical University Hospital (JP)
- The University of Osaka (JP)
Publication Details
- Journal
- Circulation Journal
- Published
- 2026-04-30
- DOI
- https://doi.org/10.1253/circj.cj-26-0033
- Primary Topic
- Atrial Fibrillation Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00