The trypanosomatid dynamin-like protein associates with glycosomes
DLP1 causes an increase cytoplasmic vesicles and altered permeability of glycosomal membranes. These results suggest that the multifunctional DLP of trypanosomatids plays a role in glycosome maintenance. Author Summary: causes changes in glycosomes, supporting a role in organelle maintenance. Dynamin-like proteins likely regulate organelle structure and function, allowing parasites to adapt to different energetic requirements during their life cycle.
Authors
- Blyssalyn V. Bieber (ORCID: https://orcid.org/0009-0007-2771-8791)
- Hsin‐Yao Tang (ORCID: https://orcid.org/0000-0003-1838-018X)
- Madeline F. Malfara (ORCID: https://orcid.org/0000-0003-2232-4551)
- Thomas Beer
- Rodolpho O. O. Souza
- Megan L. Povelones (ORCID: https://orcid.org/0000-0003-2612-6413)
Institutions
- The Wistar Institute (US)
- University at Buffalo, State University of New York (US)
- Villanova University (US)
Publication Details
- Journal
- bioRxiv (Cold Spring Harbor Laboratory)
- Published
- 2026-04-29
- DOI
- https://doi.org/10.64898/2026.04.27.721030
- Primary Topic
- Trypanosoma species research and implications
- Type
- article
- Field-Weighted Citation Impact
- 0.00