SUSTAINED-RELEASE DOSAGE FORMS: PRINCIPLES, TECHNOLOGIES AND THERAPEUTIC SIGNIFICANCE

Sustained-release (SR) dosage forms are pharmaceutical formulations designed to release a drug at a predetermined rate in order to maintain a constant drug concentration in systemic circulation for a prolonged period. These systems reduce dosing frequency, improve patient compliance, and maintain therapeutic drug levels while minimizing fluctuations associated with conventional dosage forms. This article discusses the principles, mechanisms, formulation approaches, advantages, limitations, and current advancements in sustained-release drug delivery systems.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2026-05-01
DOI
https://doi.org/10.5281/zenodo.20019689
Primary Topic
Inhalation and Respiratory Drug Delivery
Type
article
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article

SUSTAINED-RELEASE DOSAGE FORMS: PRINCIPLES, TECHNOLOGIES AND THERAPEUTIC SIGNIFICANCE

Dr. Amit Sharma2 Abhishek Raj*1
Zenodo (CERN European Organization for Nuclear Research)
Inhalation and Respiratory Drug Delivery
article

SUSTAINED-RELEASE DOSAGE FORMS: PRINCIPLES, TECHNOLOGIES AND THERAPEUTIC SIGNIFICANCE

Dr. Amit Sharma2 Abhishek Raj*1
article en

Abstract

Sustained-release (SR) dosage forms are pharmaceutical formulations designed to release a drug at a predetermined rate in order to maintain a constant drug concentration in systemic circulation for a prolonged period. These systems reduce dosing frequency, improve patient compliance, and maintain therapeutic drug levels while minimizing fluctuations associated with conventional dosage forms. This article discusses the principles, mechanisms, formulation approaches, advantages, limitations, and current advancements in sustained-release drug delivery systems.

Zenodo (CERN European Organization for Nuclear Research)
Good health and well-being
Openalex Percentile: Top 10%
Inhalation and Respiratory Drug Delivery
DOIOpen Access PDFOpenAlex
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SUSTAINED-RELEASE DOSAGE FORMS: PRINCIPLES, TECHNOLOGIES AND THERAPEUTIC SIGNIFICANCE — Dr. Amit Sharma2 Abhishek Raj*1 · Zenodo (CERN European Organization for Nuclear Research) (2026) | TGRS Research Map | TGRS