Fever of Unknown Origin in a Girl with Idiopathic Generalized Anhidrosis Diagnosed Based on a Discrepancy between Deep Body Temperature and Surface Body Temperature: A Case Report

Patients with acquired idiopathic generalized anhidrosis (AIGA) present with reduced sweating and impaired thermoregulation, which causes body temperature to increase quickly during exercise or in a hot environment. A 14-year-old girl was admitted with a variety of symptoms and prolonged fever of unknown origin. AIGA was diagnosed because of a discrepancy between deep body temperature (tympanic membrane) and body surface temperature (axillary), and she was treated. Careful history taking and physical examination are essential for patients with fever of unknown origin.