Identification of CD14 as a Potential Biomarker Relating to PANoptosis in Chronic Obstructive Pulmonary Disease
Background: The processes of pyroptosis, apoptosis, and necroptosis (PANoptosis) play a crucial role in the development of chronic obstructive pulmonary disease (COPD). Our objective is to explore potential PANoptosis-related genes in COPD. Methods: were predicted using the Drug-Gene Interaction Database (DGIdb). Results: -VB-201, LOVASTATIN, and IC143-were predicted. Conclusion: as a marker gene associating with PANoptosis in COPD, providing new ideas for clinical diagnosis and drug design of COPD.
Authors
- Shenglong Lv
- Shangkun Cai
- Xiaotian Zhang (ORCID: https://orcid.org/0000-0002-0126-6834)
- Jiawei Dong
- Yiwei Zhang
- Jian Yang (ORCID: https://orcid.org/0009-0005-3925-845X)
- Meng Zhang (ORCID: https://orcid.org/0000-0002-0738-7899)
- Xue Fu
Institutions
- Hebei Medical University (CN)
- Third Hospital of Hebei Medical University (CN)
Publication Details
- Journal
- International Journal of COPD
- Published
- 2026-04-30
- DOI
- https://doi.org/10.2147/copd.s577042
- Primary Topic
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00