Large language surgery in the era of AI and digital standards

Surgeons are increasingly encountering artificial intelligence (AI) across the research to practice continuum. In surgical settings, this includes computer vision applied to imaging and operative video, predictive modeling for perioperative risk and outcomes, and large language models that generate and transform clinical data. The potential gains are substantial, but translation has so far outpaced methodological consistency, reporting quality, and readiness for safe adoption. These gaps matter particularly in surgery, where performance is both operator and environment-dependent, and where digital and visual data are central to decision making and intervention delivery. This review maps where AI can integrate along the surgical pathway and uses the translational continuum as a framework, from problem specification and model development through clinical evaluation, reporting, and implementation. We describe how the expanding standard ecosystem can strengthen surgical AI evidence by improving transparency, reproducibility, and interpretability, and by supporting more consistent critical appraisal. We also outline why generative systems warrant additional scrutiny, given output variability, hallucinations, and rapid update cycles. A lifecycle, standards-led approach offers a practical route to more effective and safer clinical adoption.

Authors

Institutions

Publication Details

Journal
International Journal of Surgery
Published
2026-04-29
DOI
https://doi.org/10.1097/js9.0000000000005360
Primary Topic
Artificial Intelligence in Healthcare and Education
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Large language surgery in the era of AI and digital standards

Ahmad Guni, Gary S. Collins, Hutan Ashrafian, Ara Darzi
International Journal of Surgery
Artificial Intelligence in Healthcare and Education
article

Large language surgery in the era of AI and digital standards

Ahmad Guni, Gary S. Collins, Hutan Ashrafian, Ara Darzi
article en

Abstract

Surgeons are increasingly encountering artificial intelligence (AI) across the research to practice continuum. In surgical settings, this includes computer vision applied to imaging and operative video, predictive modeling for perioperative risk and outcomes, and large language models that generate and transform clinical data. The potential gains are substantial, but translation has so far outpaced methodological consistency, reporting quality, and readiness for safe adoption. These gaps matter particularly in surgery, where performance is both operator and environment-dependent, and where digital and visual data are central to decision making and intervention delivery. This review maps where AI can integrate along the surgical pathway and uses the translational continuum as a framework, from problem specification and model development through clinical evaluation, reporting, and implementation. We describe how the expanding standard ecosystem can strengthen surgical AI evidence by improving transparency, reproducibility, and interpretability, and by supporting more consistent critical appraisal. We also outline why generative systems warrant additional scrutiny, given output variability, hallucinations, and rapid update cycles. A lifecycle, standards-led approach offers a practical route to more effective and safer clinical adoption.

International Journal of Surgery
University Hospitals Birmingham NHS Foundation Trust (GB), NIHR Birmingham Biomedical Research Centre (GB), Imperial College London (GB), University of Birmingham (GB)
Openalex Percentile: Top 11%
Artificial Intelligence in Healthcare and Education
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.