Chemodivergent C–H Activation and C–C Coupling between Indoles and Alkyne-Tethered <i>N</i> -Cyanosulfonamides via Substrate-Controlled Group Migration

-cyanosulfonamide, affording C-H olefination or heteroarylation, respectively. The reaction enables one-pot construction of multiple chemical bonds, exhibits broad functional group tolerance, and is accompanied by mechanistic studies.

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Publication Details

Journal
Organic Letters
Published
2026-05-02
DOI
https://doi.org/10.1021/acs.orglett.6c00892
Primary Topic
Catalytic C–H Functionalization Methods
Type
article
Field-Weighted Citation Impact
0.00

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article

Chemodivergent C–H Activation and C–C Coupling between Indoles and Alkyne-Tethered N -Cyanosulfonamides via Substrate-Controlled Group Migration

Panjie Hu, X.C. Li, Jinlei Wang, Fen Wang
Organic Letters
Catalytic C–H Functionalization Methods
article

Chemodivergent C–H Activation and C–C Coupling between Indoles and Alkyne-Tethered N -Cyanosulfonamides via Substrate-Controlled Group Migration

Panjie Hu, X.C. Li, Jinlei Wang, Fen Wang
article en

Abstract

-cyanosulfonamide, affording C-H olefination or heteroarylation, respectively. The reaction enables one-pot construction of multiple chemical bonds, exhibits broad functional group tolerance, and is accompanied by mechanistic studies.

Organic Letters
Zhoukou Normal University (CN), Shaanxi Normal University (CN)
Zhoukou Normal University, National Natural Science Foundation of China, Natural Science Foundation of Henan Province, Henan Provincial Science and Technology Research Project
Openalex Percentile: Top 13%
Catalytic C–H Functionalization Methods
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