From ‘junk’ to medicine: the therapeutic potential of dark transcriptome-derived long noncoding RNA

“Being creative about what we can deliver with LNPs is critical...” Jokūbas Leikauskas, Editor, Nucleic Acid Insights, speaks with Omar F Khan, Assistant Professor in BME and Immunology, Canada Research Chair in Nucleic Acid Therapeutics, University of Toronto, about the emerging field of dark transcriptome medicines, the therapeutic potential of long noncoding RNA, and the critical role of lipid nanoparticle delivery systems in realizing their clinical promise.

Authors

Institutions

Publication Details

Journal
Nucleic Acid Insights
Published
2026-04-29
DOI
https://doi.org/10.18609/nuc.2026.022
Primary Topic
RNA Interference and Gene Delivery
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

From ‘junk’ to medicine: the therapeutic potential of dark transcriptome-derived long noncoding RNA

Omar F. Khan
Nucleic Acid Insights
RNA Interference and Gene Delivery
article

From ‘junk’ to medicine: the therapeutic potential of dark transcriptome-derived long noncoding RNA

Omar F. Khan
article en

Abstract

“Being creative about what we can deliver with LNPs is critical...” Jokūbas Leikauskas, Editor, Nucleic Acid Insights, speaks with Omar F Khan, Assistant Professor in BME and Immunology, Canada Research Chair in Nucleic Acid Therapeutics, University of Toronto, about the emerging field of dark transcriptome medicines, the therapeutic potential of long noncoding RNA, and the critical role of lipid nanoparticle delivery systems in realizing their clinical promise.

Nucleic Acid InsightsVol. 3(3)
University of Toronto (CA)
Openalex Percentile: Top 9%
RNA Interference and Gene Delivery
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.