A Case of Hyalinizing Clear-cell Carcinoma With EWSR1–ATF1 Fusion Gene Arising From the Minor Salivary Gland of the Tongue

Background/Aim: fusion. Case Report: fusion. Perifocal stroma showed marked hyalinization. These findings support a diagnosis of HCCC with hyalinization. The patient remained disease-free 5 years after surgery. Conclusion: This case highlights the diagnostic importance of integrating histopathology, immunoprofiling, and molecular analysis in patients with rare salivary gland tumors and underscores the favorable outcomes of complete surgical resection for HCCC of the tongue.

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Publication Details

Journal
Cancer Diagnosis & Prognosis
Published
2026-05-01
DOI
https://doi.org/10.21873/cdp.10558
Primary Topic
Salivary Gland Tumors Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
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article

A Case of Hyalinizing Clear-cell Carcinoma With EWSR1–ATF1 Fusion Gene Arising From the Minor Salivary Gland of the Tongue

Junya Ono, Haruka Takahashi, Yosuke Kikuchi, Kaname Sakuma et al.
Cancer Diagnosis & Prognosis
Salivary Gland Tumors Diagnosis and Treatment
article

A Case of Hyalinizing Clear-cell Carcinoma With EWSR1–ATF1 Fusion Gene Arising From the Minor Salivary Gland of the Tongue

Junya Ono, Haruka Takahashi, Yosuke Kikuchi, Kaname Sakuma, Daichi Hanada, AKIRA TANAKA, YASUO OKADA, SHUJI TOYA
article en

Abstract

Background/Aim: fusion. Case Report: fusion. Perifocal stroma showed marked hyalinization. These findings support a diagnosis of HCCC with hyalinization. The patient remained disease-free 5 years after surgery. Conclusion: This case highlights the diagnostic importance of integrating histopathology, immunoprofiling, and molecular analysis in patients with rare salivary gland tumors and underscores the favorable outcomes of complete surgical resection for HCCC of the tongue.

Cancer Diagnosis & PrognosisVol. 6(3)
Nippon Dental University (JP)
Zero hunger
Openalex Percentile: Top 14%
Salivary Gland Tumors Diagnosis and Treatment
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