Motor deficits after herpes zoster: a comparative analysis of patient characteristics and sensory changes

Introduction: The objective of this study was to further characterize patients with HZ-related motor deficits and to explore potential risk factors. Methods: This retrospective cohort study in the tertiary pain clinic of the University Medical Center Utrecht, includes a comparative analysis of patients presenting with and without motor deficit resulting from HZ. Patient characteristics including psychological distress were assessed using standardized questionnaires, and Quantitative Sensory Testing outcomes were analysed between the 2 groups. Results: = 0.017). Conclusion: Motor deficit may be more common than we realize and is a serious complication of HZ. Patients who experienced motor deficit as a complication of herpes zoster demonstrated more severe nerve damage, with sensory loss being the most frequent sensory phenotype. More awareness is needed for this serious complication accompanied with research guiding treatment and rehabilitation protocols.

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Publication Details

Journal
PAIN Reports
Published
2026-04-29
DOI
https://doi.org/10.1097/pr9.0000000000001440
Primary Topic
Herpesvirus Infections and Treatments
Type
article
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article

Motor deficits after herpes zoster: a comparative analysis of patient characteristics and sensory changes

Lisette M. Vernooij, Elisabeth J. M. Adriaansen, Jacqueline F.M. van Dijk, Mienke Rijsdijk et al.
PAIN Reports
Herpesvirus Infections and Treatments
article

Motor deficits after herpes zoster: a comparative analysis of patient characteristics and sensory changes

Lisette M. Vernooij, Elisabeth J. M. Adriaansen, Jacqueline F.M. van Dijk, Mienke Rijsdijk, Bart J.H. Splinter, Frank J.P.M. Huygen
article en

Abstract

Introduction: The objective of this study was to further characterize patients with HZ-related motor deficits and to explore potential risk factors. Methods: This retrospective cohort study in the tertiary pain clinic of the University Medical Center Utrecht, includes a comparative analysis of patients presenting with and without motor deficit resulting from HZ. Patient characteristics including psychological distress were assessed using standardized questionnaires, and Quantitative Sensory Testing outcomes were analysed between the 2 groups. Results: = 0.017). Conclusion: Motor deficit may be more common than we realize and is a serious complication of HZ. Patients who experienced motor deficit as a complication of herpes zoster demonstrated more severe nerve damage, with sensory loss being the most frequent sensory phenotype. More awareness is needed for this serious complication accompanied with research guiding treatment and rehabilitation protocols.

PAIN ReportsVol. 11(3)
Utrecht University (NL), Erasmus MC (NL), University Medical Center Utrecht (NL), Martini Ziekenhuis (NL), Erasmus University Rotterdam (NL)
Openalex Percentile: Top 12%
Herpesvirus Infections and Treatments
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Motor deficits after herpes zoster: a comparative analysis of patient characteristics and sensory changes — Lisette M. Vernooij, Elisabeth J. M. Adriaansen, et al. · PAIN Reports (2026) | TGRS Research Map | TGRS