Diffuse Large B‐Cell Lymphoma With Pulmonary and Gastric Involvement Mimicking Nontuberculous Mycobacterial Lung Disease

, and partial spontaneous regression of several nodules initially supported a diagnosis of nontuberculous mycobacterial lung disease. However, other nodules showed progressive enlargement during antimicrobial therapy. Surgical lung biopsy revealed diffuse large B-cell lymphoma (DLBCL), and subsequent evaluation demonstrated gastric involvement. The patient achieved complete remission after systemic chemotherapy. This case highlights the diagnostic challenge of pulmonary lymphoma presenting with heterogeneous radiological behaviour and emphasizes the importance of histological confirmation when the clinical course is atypical.

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Publication Details

Journal
Respirology Case Reports
Published
2026-04-30
DOI
https://doi.org/10.1002/rcr2.70601
Primary Topic
Mycobacterium research and diagnosis
Type
article
Field-Weighted Citation Impact
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article

Diffuse Large B‐Cell Lymphoma With Pulmonary and Gastric Involvement Mimicking Nontuberculous Mycobacterial Lung Disease

Kazuhiro Asada, Daisuke Akahori, Yuu Saitoh, Satoru Morita et al.
Respirology Case Reports
Mycobacterium research and diagnosis
article

Diffuse Large B‐Cell Lymphoma With Pulmonary and Gastric Involvement Mimicking Nontuberculous Mycobacterial Lung Disease

Kazuhiro Asada, Daisuke Akahori, Yuu Saitoh, Satoru Morita, Kosuke Suzuki, Emi Fukasawa, Kosuke Masuda, Akito Yamamoto, Taisuke Akamatsu, Toshihiro Shirai, Yumi Fujita, Makoto Suzuki, Sho Murai, Mika Saigusa
article en

Abstract

, and partial spontaneous regression of several nodules initially supported a diagnosis of nontuberculous mycobacterial lung disease. However, other nodules showed progressive enlargement during antimicrobial therapy. Surgical lung biopsy revealed diffuse large B-cell lymphoma (DLBCL), and subsequent evaluation demonstrated gastric involvement. The patient achieved complete remission after systemic chemotherapy. This case highlights the diagnostic challenge of pulmonary lymphoma presenting with heterogeneous radiological behaviour and emphasizes the importance of histological confirmation when the clinical course is atypical.

Respirology Case ReportsVol. 14(5)
Shizuoka General Hospital (JP)
Good health and well-being
Openalex Percentile: Top 12%
Mycobacterium research and diagnosis
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