Characteristic Clinical Features of Melanoma in Patients With Excised Skin Lesions

Background/Aim: The aim of this study was to assess the risk of melanoma in patients with excised skin lesions (ESLs) considering their clinical features. Patients and Methods: A total of 126 cases of ESLs were collected between December 2021 and April 2025. The clinical features of 109 benign skin lesions (BSLs), 10 non-nodular melanomas (NNMs), and seven nodular melanomas (NMs) were analyzed according to the ABCDE criteria, the ABCDE-EFG method, and the 7-point checklist (7-PCL) scale. Results: =0.027) were also found to be significant in differentiating for both NNMs and NMs compared to BSLs. However, in multivariate analysis, for NMs alone, no clinical features were significantly more frequent compared to BSLs. Conclusion: , color variegation and evolution in size, shape or color within six months, but not for NMs cases alone in the Firth's penalized logistic regression.

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Publication Details

Journal
Cancer Diagnosis & Prognosis
Published
2026-05-01
DOI
https://doi.org/10.21873/cdp.10540
Primary Topic
Cutaneous Melanoma Detection and Management
Type
article
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article

Characteristic Clinical Features of Melanoma in Patients With Excised Skin Lesions

OLIWIA MAJEWSKA, Anna Markiewicz, Piotr Kulig, Paweł Brzewski et al.
Cancer Diagnosis & Prognosis
Cutaneous Melanoma Detection and Management
article

Characteristic Clinical Features of Melanoma in Patients With Excised Skin Lesions

OLIWIA MAJEWSKA, Anna Markiewicz, Piotr Kulig, Paweł Brzewski, Jan Kulig
article en

Abstract

Background/Aim: The aim of this study was to assess the risk of melanoma in patients with excised skin lesions (ESLs) considering their clinical features. Patients and Methods: A total of 126 cases of ESLs were collected between December 2021 and April 2025. The clinical features of 109 benign skin lesions (BSLs), 10 non-nodular melanomas (NNMs), and seven nodular melanomas (NMs) were analyzed according to the ABCDE criteria, the ABCDE-EFG method, and the 7-point checklist (7-PCL) scale. Results: =0.027) were also found to be significant in differentiating for both NNMs and NMs compared to BSLs. However, in multivariate analysis, for NMs alone, no clinical features were significantly more frequent compared to BSLs. Conclusion: , color variegation and evolution in size, shape or color within six months, but not for NMs cases alone in the Firth's penalized logistic regression.

Cancer Diagnosis & PrognosisVol. 6(3)
Jagiellonian University (PL), John Paul II Hospital (PL), Andrzej Frycz Modrzewski Krakow University (PL), Krakow Cardiovascular Research Institute (PL)
Zero hunger
Openalex Percentile: Top 15%
Cutaneous Melanoma Detection and Management
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Characteristic Clinical Features of Melanoma in Patients With Excised Skin Lesions — OLIWIA MAJEWSKA, Anna Markiewicz, et al. · Cancer Diagnosis & Prognosis (2026) | TGRS Research Map | TGRS