The role of IP3R and TRPC3 channels in vasoconstriction and hypertension
Rs and TRPC3 channels offers new insight into the dysregulated Ca²⁺ signaling underlying hypertension. Targeting this coupling mechanism may represent a novel therapeutic strategy to restore vascular homeostasis and reduce blood pressure in affected individuals.
Authors
- Quiara Lovatti Alves (ORCID: https://orcid.org/0000-0001-7757-8407)
- Liliane Barreto da Silva (ORCID: https://orcid.org/0000-0002-1039-9831)
- Raiana dos Anjos Moraes (ORCID: https://orcid.org/0000-0001-9484-8157)
- Rafael Leonne Cruz de Jesus
- Darízy Flávia Silva
Institutions
- Universidade Federal da Bahia (BR)
- University of South Carolina (US)
- National Institute of Science and Technology (ID)
Publication Details
- Journal
- Pflügers Archiv - European Journal of Physiology
- Published
- 2026-05-01
- DOI
- https://doi.org/10.1007/s00424-026-03175-y
- Primary Topic
- Ion Channels and Receptors
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Fundação Oswaldo Cruz