Design, Synthesis, and Antifungal Evaluation of Novel α-Methylene-γ-Butyrolactone Derivatives Bearing a Diaryl Ether Moiety for Phytopathogen Control

exerts its bioactivity primarily by binding to respiratory chain complex III, thereby inhibiting mitochondrial ATP synthesis and impairing fungal energy metabolism. This work provides valuable insights for the development of MBL derivatives incorporating a diaryl ether moiety as promising novel agricultural fungicidal and bactericidal agents.

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Publication Details

Journal
Journal of Agricultural and Food Chemistry
Published
2026-05-02
DOI
https://doi.org/10.1021/acs.jafc.6c00722
Primary Topic
Fungal Plant Pathogen Control
Type
article
Field-Weighted Citation Impact
0.00

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article

Design, Synthesis, and Antifungal Evaluation of Novel α-Methylene-γ-Butyrolactone Derivatives Bearing a Diaryl Ether Moiety for Phytopathogen Control

Xingyu Ren, L. Li, Guangyou Chen, Heng Li et al.
Journal of Agricultural and Food Chemistry
Fungal Plant Pathogen Control
article

Design, Synthesis, and Antifungal Evaluation of Novel α-Methylene-γ-Butyrolactone Derivatives Bearing a Diaryl Ether Moiety for Phytopathogen Control

Xingyu Ren, L. Li, Guangyou Chen, Heng Li, Zhiqing Ma, Juntao Feng, Yong Wang, Keman Li, Peng Lei, Deyou Yang
article en

Abstract

exerts its bioactivity primarily by binding to respiratory chain complex III, thereby inhibiting mitochondrial ATP synthesis and impairing fungal energy metabolism. This work provides valuable insights for the development of MBL derivatives incorporating a diaryl ether moiety as promising novel agricultural fungicidal and bactericidal agents.

Journal of Agricultural and Food Chemistry
Institute of Plant Protection (CN), Shanghai Pesticide Research Institute (CN), Plant Protection Institute (HU), University of Agriculture Faisalabad (PK), Northwest A&F University (CN)
National Key Research and Development Program of China, Key Research and Development Projects of Shaanxi Province
Openalex Percentile: Top 7%
Fungal Plant Pathogen Control
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Design, Synthesis, and Antifungal Evaluation of Novel α-Methylene-γ-Butyrolactone Derivatives Bearing a Diaryl Ether Moiety for Phytopathogen Control — Xingyu Ren, L. Li, et al. · Journal of Agricultural and Food Chemistry (2026) | TGRS Research Map | TGRS