Serositis as possible manifestation in MDS/AML patients with complex karyotype and TP53 mutation: case series
Myelodysplastic syndromes (MDS) and Acute Myeloid Leukemia (AML) are increasingly recognized to exhibit immune dysregulation, which can occasionally present with autoinflammatory manifestations. We describe four patients with MDS/AML harboring p53 mutations and a complex karyotype who developed inflammatory serositis without infectious correlation. All patients showed clinical improvement following corticosteroid therapy.
Authors
- Isacco Ferrarini (ORCID: https://orcid.org/0000-0001-9867-8335)
- Chiara Colato
- Mauro Krampera (ORCID: https://orcid.org/0000-0002-7280-2040)
- Edoardo Tamellini
- Pietro Antonini
- Nicola Serafin
- Eleonora Gugole
- Ilaria Tanasi
- Sara Jance
Institutions
- University of Verona (IT)
- Azienda Ospedaliera Universitaria Integrata Verona (IT)
Publication Details
- Journal
- Annals of Hematology
- Published
- 2026-05-02
- DOI
- https://doi.org/10.1007/s00277-026-06960-y
- Primary Topic
- Acute Myeloid Leukemia Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00