Racial disparities in pulse oximetry: measurement bias and clinical implications—a systematic review

This review synthesised existing evidence on racial disparities in pulse oximeter accuracy, quantified the degree of bias, evaluated clinical effects, highlighted implications for practice, and identified research priorities needed to achieve equitable device performance. While prior systematic reviews have examined pulse oximeter accuracy across varying skin pigmentation levels, most have focused primarily on aggregate accuracy metrics without integrating downstream clinical consequences or anaesthesiology-specific implications. In contrast, this review synthesises paired SpO₂–SaO₂ comparisons stratified by race or skin tone and explicitly links measurement bias to occult hypoxaemia, treatment escalation thresholds, and perioperative decision-making. By integrating device-level performance characteristics with clinical risk pathways, this review aims to provide actionable insights for anaesthesiologists and critical care clinicians.

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Publication Details

Journal
Frontiers in Anesthesiology
Published
2026-04-30
DOI
https://doi.org/10.3389/fanes.2026.1796674
Primary Topic
Non-Invasive Vital Sign Monitoring
Type
article
Field-Weighted Citation Impact
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article

Racial disparities in pulse oximetry: measurement bias and clinical implications—a systematic review

Adeniyi Kazeem Akiseku, Oluwayemisi Esther Ekor, Samuel Ankamah, Suzetta Naa-Norley Brocke
Frontiers in Anesthesiology
Non-Invasive Vital Sign Monitoring
article

Racial disparities in pulse oximetry: measurement bias and clinical implications—a systematic review

Adeniyi Kazeem Akiseku, Oluwayemisi Esther Ekor, Samuel Ankamah, Suzetta Naa-Norley Brocke
article en

Abstract

This review synthesised existing evidence on racial disparities in pulse oximeter accuracy, quantified the degree of bias, evaluated clinical effects, highlighted implications for practice, and identified research priorities needed to achieve equitable device performance. While prior systematic reviews have examined pulse oximeter accuracy across varying skin pigmentation levels, most have focused primarily on aggregate accuracy metrics without integrating downstream clinical consequences or anaesthesiology-specific implications. In contrast, this review synthesises paired SpO₂–SaO₂ comparisons stratified by race or skin tone and explicitly links measurement bias to occult hypoxaemia, treatment escalation thresholds, and perioperative decision-making. By integrating device-level performance characteristics with clinical risk pathways, this review aims to provide actionable insights for anaesthesiologists and critical care clinicians.

Frontiers in AnesthesiologyVol. 5
University of Cape Coast (GH), Emmanuel College - Massachusetts (US), National Postgraduate Medical College of Nigeria (NG)
Peace, Justice and strong institutions
Openalex Percentile: Top 12%
Non-Invasive Vital Sign Monitoring
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