Envisaging the Molecular Foot Printing of Anti-Protozoal Drug Emetine Binding to Lysozyme by Confocal Raman Scattering and X-ray Crystallography
) or tertiary structure upon emetine binding. Together, these findings demonstrate the utility of Raman spectroscopy as a valuable complementary tool for assessing ligand incorporation within protein crystals and probing protein-ligand interactions.
Authors
- Sandip Dolui (ORCID: https://orcid.org/0000-0003-1540-5062)
- Shubham Kundu (ORCID: https://orcid.org/0000-0003-4409-462X)
- Saumen Datta (ORCID: https://orcid.org/0000-0002-3638-9383)
- Nakul C. Maiti (ORCID: https://orcid.org/0000-0002-8498-6502)
- Basavraj Khanppnavar (ORCID: https://orcid.org/0000-0002-6637-3550)
- Koushik Nayak
- Prasenjit Naskar
- Anupam Roy
- Bidisha Chakraborty
Institutions
- Indian Institute of Chemical Biology (IN)
- Ramakrishna Mission Vidyamandira (IN)
- Adamas University (IN)
- Ramakrishna Mission Vivekananda Educational and Research Institute (IN)
- Human Resource Development Center (BG)
- West Bengal State University (IN)
- Council of Scientific and Industrial Research (IN)
- Academy of Scientific and Innovative Research (IN)
Publication Details
- Journal
- The Journal of Physical Chemistry B
- Published
- 2026-05-01
- DOI
- https://doi.org/10.1021/acs.jpcb.5c07874
- Primary Topic
- Enzyme Structure and Function
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Council of Scientific and Industrial Research, India
- University Grants Commission