Case Report: Ophthalmic endoscopy for complete resection of a symptomatic iris pigment epithelial cyst

Background To report a case of symptomatic posterior iris pigment epithelial (IPE) cyst causing angle closure that was successfully managed with ophthalmic endoscopy. Case presentation A female with a 1-week history of blurred vision in right eye (RE). Slit lamp and UBM examination revealed iris cysts in both eyes, and a large dominant temporal cyst in the RE produced mild forward displacement of the ciliary body and bulging of the iris root. Diagnosis was iris cyst in both eyes. Assisted by ophthalmic endoscopy, the cyst wall was removed completely without damaging the surrounding tissues or the lens. On postoperative day one, the patient’s best-corrected visual acuity (BCVA) improved, and her intraocular pressure (IOP) decreased. At the 3-months follow-up, the patient’s BCVA and IOP remained stable, and there was no cyst recurrence. Conclusion This case suggests that endoscopic iridocystectomy is a good, viable, and minimally invasive option to treat symptomatic iris cysts.

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Publication Details

Journal
Frontiers in Medicine
Published
2026-04-30
DOI
https://doi.org/10.3389/fmed.2026.1807287
Primary Topic
Ocular Oncology and Treatments
Type
article
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article

Case Report: Ophthalmic endoscopy for complete resection of a symptomatic iris pigment epithelial cyst

Xing Du, X C Wang, M M Wang, Yuan Tao et al.
Frontiers in Medicine
Ocular Oncology and Treatments
article

Case Report: Ophthalmic endoscopy for complete resection of a symptomatic iris pigment epithelial cyst

Xing Du, X C Wang, M M Wang, Yuan Tao, Chenming Zhang
article en

Abstract

Background To report a case of symptomatic posterior iris pigment epithelial (IPE) cyst causing angle closure that was successfully managed with ophthalmic endoscopy. Case presentation A female with a 1-week history of blurred vision in right eye (RE). Slit lamp and UBM examination revealed iris cysts in both eyes, and a large dominant temporal cyst in the RE produced mild forward displacement of the ciliary body and bulging of the iris root. Diagnosis was iris cyst in both eyes. Assisted by ophthalmic endoscopy, the cyst wall was removed completely without damaging the surrounding tissues or the lens. On postoperative day one, the patient’s best-corrected visual acuity (BCVA) improved, and her intraocular pressure (IOP) decreased. At the 3-months follow-up, the patient’s BCVA and IOP remained stable, and there was no cyst recurrence. Conclusion This case suggests that endoscopic iridocystectomy is a good, viable, and minimally invasive option to treat symptomatic iris cysts.

Frontiers in MedicineVol. 13
Fourth People’s Hospital of Jinan (CN), Second Hospital of Shandong University (CN)
Openalex Percentile: Top 7%
Ocular Oncology and Treatments
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