Establishing standards for genome wide association studies in eusocial insects through a case study in honey bees

and sample sizes of at least 1,000 are effective for identifying QTL for key traits. Including both queen and worker genotypes improved QTL discovery power, emphasizing the need to optimize GWAS methods for eusocial species. Our results should improve future GWAS in honey bees and highlights the need for additional simulations and standard-setting work in other eusocial species.

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Journal
Scientific Reports
Published
2026-05-01
DOI
https://doi.org/10.1038/s41598-026-51476-0
Primary Topic
Insect and Arachnid Ecology and Behavior
Type
article
Field-Weighted Citation Impact
0.00

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article

Establishing standards for genome wide association studies in eusocial insects through a case study in honey bees

Jana Obšteter, Mulusew Fikere, Brock A. Harpur, Gregor Gorjanc et al.
Scientific Reports
Insect and Arachnid Ecology and Behavior
article

Establishing standards for genome wide association studies in eusocial insects through a case study in honey bees

Jana Obšteter, Mulusew Fikere, Brock A. Harpur, Gregor Gorjanc, Dylan Ryals, Luiz F Brito
article en

Abstract

and sample sizes of at least 1,000 are effective for identifying QTL for key traits. Including both queen and worker genotypes improved QTL discovery power, emphasizing the need to optimize GWAS methods for eusocial species. Our results should improve future GWAS in honey bees and highlights the need for additional simulations and standard-setting work in other eusocial species.

Scientific Reports
Roslin Institute (GB), Purdue University West Lafayette (US), Agricultural institute of Slovenia (SI), University of Edinburgh (GB)
U.S. Department of Agriculture
Life in Land
Openalex Percentile: Top 12%
Insect and Arachnid Ecology and Behavior
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