Therapeutic Challenges in Case of <i>Trichophyton indotineae</i> Dermatophytosis, Singapore, 2025

Trichophyton indotineae is an emerging dermatophyte frequently associated with terbinafine resistance. We report a case of recalcitrant T. indotineae infection in Singapore with limited response despite prolonged azole therapy, which only resolved after combination therapy with anidulafungin and itraconazole. This case highlights therapeutic challenges and need for improved diagnostics in T. indotineae infections.

Authors

Publication Details

Journal
Emerging infectious diseases
Published
2026-05-01
DOI
https://doi.org/10.3201/eid3206.251606
Primary Topic
Nail Diseases and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Therapeutic Challenges in Case of Trichophyton indotineae Dermatophytosis, Singapore, 2025

Lester Juay, Matthew Chung Yi Koh, Tiara Joy Foo, Sean Jiawei Wu et al.
Emerging infectious diseases
Nail Diseases and Treatments
article

Therapeutic Challenges in Case of Trichophyton indotineae Dermatophytosis, Singapore, 2025

Lester Juay, Matthew Chung Yi Koh, Tiara Joy Foo, Sean Jiawei Wu, Ka Lip Chew
article en

Abstract

Trichophyton indotineae is an emerging dermatophyte frequently associated with terbinafine resistance. We report a case of recalcitrant T. indotineae infection in Singapore with limited response despite prolonged azole therapy, which only resolved after combination therapy with anidulafungin and itraconazole. This case highlights therapeutic challenges and need for improved diagnostics in T. indotineae infections.

Emerging infectious diseasesVol. 32(6)
Good health and well-being
Openalex Percentile: Top 12%
Nail Diseases and Treatments
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