Characterisation, Biological Screening and Efficient Ultrasound Synthesis of New Cyclic β-Diketones

Using a straightforward and practical technique, 1-(2-Hydroxyphenyl)-3-propane,1,3-diones 4(L1-L3) were created by applying the Baker-Venkatraman transformation to the matching 2-acetylphenyl benzoate using both conventional and ultrasonic irradiation. Spectral analysis, including IR, 1H NMR, 13C NMR, UV/Vis, mass, and elemental analysis, has been used to assign the structure of synthetic substances. The antibacterial and antifungal properties of the produced compounds were assessed. From an economic and environmental standpoint, this manipulation is highly intriguing due to the use of ultrasonic irradiation, straightforward reaction conditions, separation, and purification.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2026-04-25
DOI
https://doi.org/10.5281/zenodo.19755999
Primary Topic
Ultrasound and Cavitation Phenomena
Type
article
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article

Characterisation, Biological Screening and Efficient Ultrasound Synthesis of New Cyclic β-Diketones

Shyam Takle
Zenodo (CERN European Organization for Nuclear Research)
Ultrasound and Cavitation Phenomena
article

Characterisation, Biological Screening and Efficient Ultrasound Synthesis of New Cyclic β-Diketones

Shyam Takle
article en

Abstract

Using a straightforward and practical technique, 1-(2-Hydroxyphenyl)-3-propane,1,3-diones 4(L1-L3) were created by applying the Baker-Venkatraman transformation to the matching 2-acetylphenyl benzoate using both conventional and ultrasonic irradiation. Spectral analysis, including IR, 1H NMR, 13C NMR, UV/Vis, mass, and elemental analysis, has been used to assign the structure of synthetic substances. The antibacterial and antifungal properties of the produced compounds were assessed. From an economic and environmental standpoint, this manipulation is highly intriguing due to the use of ultrasonic irradiation, straightforward reaction conditions, separation, and purification.

Zenodo (CERN European Organization for Nuclear Research)
J. S. Ayurveda Mahavidyalaya and P.D. Patel Ayurveda Hospital (IN)
Responsible consumption and production
Openalex Percentile: Top 11%
Ultrasound and Cavitation Phenomena
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