Unveiling a flip-over retention mechanism in the gas-phase Cl− + (CH3)3CI SN2 reaction
2 reaction, where substitution occurs via the direct flipping of the tert-butyl group, leading to retention of the tetrahedral carbon center. This mechanism manifests as a predominant forward-scattering feature in the product angular distribution and provides an important perspective on substitution dynamics in organic reactions.
Authors
- Die Zhang (ORCID: https://orcid.org/0009-0005-2215-6350)
- Björn Bastian (ORCID: https://orcid.org/0000-0003-2820-8869)
- Tim Michaelsen (ORCID: https://orcid.org/0000-0002-5937-7393)
- Roland Wester (ORCID: https://orcid.org/0000-0001-7935-6066)
- Eduardo Carrascosa (ORCID: https://orcid.org/0000-0003-4338-8669)
- Xiaoxiao Lu (ORCID: https://orcid.org/0000-0003-1857-7919)
- Jennifer Meyer (ORCID: https://orcid.org/0000-0003-1303-2370)
- Lulu Li (ORCID: https://orcid.org/0000-0002-7790-090X)
- Bina Fu
Institutions
- University of Kaiserslautern (DE)
- Liaoning Normal University (CN)
- Dalian Institute of Chemical Physics (CN)
- Universität Innsbruck (AT)
- Chinese Academy of Sciences (CN)
- Hefei University (CN)
- Hefei National Center for Physical Sciences at Nanoscale (CN)
- National Science Centre (PL)
- University of Chinese Academy of Sciences (CN)
Publication Details
- Journal
- Nature Communications
- Published
- 2026-05-01
- DOI
- https://doi.org/10.1038/s41467-026-72121-4
- Primary Topic
- Advanced Chemical Physics Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Austrian Science Fund