Intestinal epithelial Syndecan-1 maintains mucosal homeostasis in inflammatory bowel disease by enhancing <i>Faecalibacterium prausnitzii</i> biofilm formation
colonization and growth through enhanced biofilm formation and cobalamin synthesis, thereby highlighting the therapeutic potential of HS for IBD and offering a new basis for host-directed microbiota regulation.
Authors
- Anjiang Wang (ORCID: https://orcid.org/0000-0001-6670-6645)
- S Z Chen
- Yue Wang (ORCID: https://orcid.org/0000-0003-0098-5359)
- Senbao Xu
- Hanxiao Feng (ORCID: https://orcid.org/0000-0001-9474-4892)
- J Huang
- Kai Sun
- Yunying Gong
- Qiujuan Ye
- Dekai Zheng
- Ye Ouyang
- Ye Chen
- Xiuying Liu
Institutions
- Nanfang Hospital (CN)
- Southern Medical University Shenzhen Hospital (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Gut Microbes
- Published
- 2026-05-01
- DOI
- https://doi.org/10.1080/19490976.2026.2665870
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Guangdong Province
- Southern Medical University
- Nanfang Hospital
- National Key Research and Development Program of China