Vagus Nerve Stimulation Paired With Tones Alters the Auditory Cortex Proteome in a Rat Model of Rett Syndrome

rats by changing the expression of proteins involved in regulating synaptic vesicles and synaptic transmission. This work provides evidence of key mechanisms that may drive auditory processing dysfunction in Rett syndrome and demonstrates that VNS-tone pairing is sufficient to alter protein expression in the auditory cortex.

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Publication Details

Journal
Developmental Neurobiology
Published
2026-04-30
DOI
https://doi.org/10.1002/dneu.70032
Primary Topic
Vagus Nerve Stimulation Research
Type
article
Field-Weighted Citation Impact
0.00

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article

Vagus Nerve Stimulation Paired With Tones Alters the Auditory Cortex Proteome in a Rat Model of Rett Syndrome

Crystal T. Engineer, Tanya T. Danaphongse, Fang Bian, Yara El Zoghby et al.
Developmental Neurobiology
Vagus Nerve Stimulation Research
article

Vagus Nerve Stimulation Paired With Tones Alters the Auditory Cortex Proteome in a Rat Model of Rett Syndrome

Crystal T. Engineer, Tanya T. Danaphongse, Fang Bian, Yara El Zoghby, Isabella K. Myers, Maria P. Solano, Diana Tavares-Ferreira
article en

Abstract

rats by changing the expression of proteins involved in regulating synaptic vesicles and synaptic transmission. This work provides evidence of key mechanisms that may drive auditory processing dysfunction in Rett syndrome and demonstrates that VNS-tone pairing is sufficient to alter protein expression in the auditory cortex.

Developmental NeurobiologyVol. 86(3)
The University of Texas at Dallas (US)
Autism Research Institute
Openalex Percentile: Top 10%
Vagus Nerve Stimulation Research
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