Mephedrene‐Induced Cardiac Electrophysiological and Molecular Alterations: An Integrated In Vitro and In Vivo Study

-regulatory mechanisms in vitro and prolongs QT intervals in vivo. These findings indicate substantial cardiovascular risk associated with mephedrene exposure and underscore the need for toxicological surveillance and regulatory action to mitigate potential public health harms posed by emerging novel psychoactive substances.

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Publication Details

Journal
Journal of Applied Toxicology
Published
2026-05-01
DOI
https://doi.org/10.1002/jat.70233
Primary Topic
Pharmacology and Obesity Treatment
Type
article
Field-Weighted Citation Impact
0.00

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article

Mephedrene‐Induced Cardiac Electrophysiological and Molecular Alterations: An Integrated In Vitro and In Vivo Study

Hyun Kyu Min, S.E.S. Lim, Ki Kyung Jung, Min Gyeong Kim
Journal of Applied Toxicology
Pharmacology and Obesity Treatment
article

Mephedrene‐Induced Cardiac Electrophysiological and Molecular Alterations: An Integrated In Vitro and In Vivo Study

Hyun Kyu Min, S.E.S. Lim, Ki Kyung Jung, Min Gyeong Kim
article en

Abstract

-regulatory mechanisms in vitro and prolongs QT intervals in vivo. These findings indicate substantial cardiovascular risk associated with mephedrene exposure and underscore the need for toxicological surveillance and regulatory action to mitigate potential public health harms posed by emerging novel psychoactive substances.

Journal of Applied Toxicology
Ministry of Food and Drug Safety (KR), Sungkyunkwan University (KR)
National Institute of Food and Drug Safety Evaluation
Good health and well-being
Openalex Percentile: Top 11%
Pharmacology and Obesity Treatment
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