A transformer-graph neural network framework for cyber twin-driven personalized respiratory monitoring

Maintaining healthy breathing is important to health and preventing serious respiratory complications, many of which can result in death. Individuals living with ongoing chronic respiratory disease (asthma, chronic obstructive pulmonary disease, sleep apnea) need ongoing personal patient-centred continuous non-hospital-based monitoring for diagnosis and appropriate treatment. Many traditional existing patient-centred physical health monitoring systems are insufficient due to their limited flexibility, combining multiple sources of sensor data that monitor patients continuously and act in real time to document health states are yet to be invented. This paper proposes a respiratory monitoring system that utilizes a cyber twin (CT) model, and a graph neural network (GNN) function for relational reasoning of the individual based on multi-source data, with a transformer architecture for long-range behaviour modifications based on time series data. The cyber twin continuously updates the physiological state of each individual and predicts what will happen if treatment occurs. This work provides complete results for the comparison of the proposed transformer GNN versus LSTM-CNN being used as evaluation frameworks for established experimental effectiveness, achieving better comparisons for the performance of the model direct interfaces. The proposed approaches provided superior performance over traditional networks with absolute error reductions of 8-13% on respiratory rate (RR) estimates, and F1 score improvements of + 3.1-6.8 points between multimodal respiratory ensembles relative to each other. A graphical figure and table show all the experimental validity and comparisons.

Authors

Institutions

Publication Details

Journal
Scientific Reports
Published
2026-04-30
DOI
https://doi.org/10.1038/s41598-026-49994-y
Primary Topic
Non-Invasive Vital Sign Monitoring
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

A transformer-graph neural network framework for cyber twin-driven personalized respiratory monitoring

Suresh Muthusamy, Choon Kit Chan, Amol S. Vedpathak, S K Mithun Bahavath et al.
Scientific Reports
Non-Invasive Vital Sign Monitoring
article

A transformer-graph neural network framework for cyber twin-driven personalized respiratory monitoring

Suresh Muthusamy, Choon Kit Chan, Amol S. Vedpathak, S K Mithun Bahavath, A Manikandan, A Nivetha, A Divyadharshini, Chandrakant Sonawane, Saurav Dixit, K Jothimani
article en

Abstract

Maintaining healthy breathing is important to health and preventing serious respiratory complications, many of which can result in death. Individuals living with ongoing chronic respiratory disease (asthma, chronic obstructive pulmonary disease, sleep apnea) need ongoing personal patient-centred continuous non-hospital-based monitoring for diagnosis and appropriate treatment. Many traditional existing patient-centred physical health monitoring systems are insufficient due to their limited flexibility, combining multiple sources of sensor data that monitor patients continuously and act in real time to document health states are yet to be invented. This paper proposes a respiratory monitoring system that utilizes a cyber twin (CT) model, and a graph neural network (GNN) function for relational reasoning of the individual based on multi-source data, with a transformer architecture for long-range behaviour modifications based on time series data. The cyber twin continuously updates the physiological state of each individual and predicts what will happen if treatment occurs. This work provides complete results for the comparison of the proposed transformer GNN versus LSTM-CNN being used as evaluation frameworks for established experimental effectiveness, achieving better comparisons for the performance of the model direct interfaces. The proposed approaches provided superior performance over traditional networks with absolute error reductions of 8-13% on respiratory rate (RR) estimates, and F1 score improvements of + 3.1-6.8 points between multimodal respiratory ensembles relative to each other. A graphical figure and table show all the experimental validity and comparisons.

Scientific Reports
INTI International University (MY), Madurai Medical College (IN), Symbiosis International University (IN), Chitkara University (IN)
Good health and well-being
Openalex Percentile: Top 13%
Non-Invasive Vital Sign Monitoring
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.