Sulfonamide DPA‐Based Mononuclear Cobalt(II) Complexes: Evaluation of ROS‐Driven Cytotoxicity

values of 95.9 µM and 91.3 µM against MDA-MB-231 and MCF-7 cells, respectively. The enhanced activity of complex 2 is likely due to its ability to generate reactive oxygen species (ROS). These findings suggest that complex 2 may serve as a superior potential scaffold for the development of cobalt-based cytotoxic agents with tunable electronic and photophysical properties.

Authors

Indrajit Roy (ORCID: https://orcid.org/0000-0002-5087-8140)
Roy Anindya (ORCID: https://orcid.org/0000-0001-8561-907X)
Manoj Kumar Kumawat (ORCID: https://orcid.org/0009-0003-1851-4923)
Nafeesa Shahnaz
Sharan Shanmuga Vuppaladadium Rathnam
Somnath Maji

Institutions

Indian Institute of Technology Hyderabad (IN)

Publication Details

Journal: Chemistry - An Asian Journal
Published: 2026-04-30
DOI: https://doi.org/10.1002/asia.70756
Primary Topic: Metal complexes synthesis and properties
Type: article
Field-Weighted Citation Impact: 0.00

Funders

Indian Council of Medical Research

Controls

|||

ALL TIME

JAN

FEB

MAR

APR

MAY

JUN

JUL

AUG

SEP

OCT

article

Sulfonamide DPA‐Based Mononuclear Cobalt(II) Complexes: Evaluation of ROS‐Driven Cytotoxicity

Indrajit Roy, Roy Anindya, Manoj Kumar Kumawat, Nafeesa Shahnaz et al.

Apr 30, 2026

Chemistry - An Asian Journal

Metal complexes synthesis and properties

article

Sulfonamide DPA‐Based Mononuclear Cobalt(II) Complexes: Evaluation of ROS‐Driven Cytotoxicity

Indrajit Roy, Roy Anindya, Manoj Kumar Kumawat, Nafeesa Shahnaz, Sharan Shanmuga Vuppaladadium Rathnam, Somnath Maji

April 30, 2026article en

Abstract

values of 95.9 µM and 91.3 µM against MDA-MB-231 and MCF-7 cells, respectively. The enhanced activity of complex 2 is likely due to its ability to generate reactive oxygen species (ROS). These findings suggest that complex 2 may serve as a superior potential scaffold for the development of cobalt-based cytotoxic agents with tunable electronic and photophysical properties.

Chemistry - An Asian JournalVol. 21(9)

Indian Institute of Technology Hyderabad (IN)

Indian Council of Medical Research

Life below water

Openalex Percentile: Top 13%

Metal complexes synthesis and properties

DOI Source OpenAlex

AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.