Quantifying the Renal Impact of [ <sup>177</sup> Lu]Lu-PSMA-617: A Longitudinal Analysis of Real-World Data from the LUMEN Registry

Lu]Lu-PSMA-617 is associated with a slight long-term average decline in eGFR. Although this is unlikely to be clinically relevant for late-stage mCRPC, the cumulative dose effect warrants careful monitoring in earlier disease stages.

Authors

Philipp Krausewitz (ORCID: https://orcid.org/0000-0002-8213-9975)
Markus Essler
Thomas Büttner (ORCID: https://orcid.org/0000-0003-0316-9621)
Jim Küppers
Milka Marinova (ORCID: https://orcid.org/0000-0002-1856-5005)
Barbara Kreppel
Leander Fritzsche
Christian Hoffmann
Florian Gärtner
Manuel Ritter

Institutions

University Hospital Bonn (DE)

Publication Details

Journal: Journal of Nuclear Medicine
Published: 2026-04-30
DOI: https://doi.org/10.2967/jnumed.125.271077
Primary Topic: Prostate Cancer Treatment and Research
Type: article
Field-Weighted Citation Impact: 0.00

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article

Quantifying the Renal Impact of [ ¹⁷⁷ Lu]Lu-PSMA-617: A Longitudinal Analysis of Real-World Data from the LUMEN Registry

Philipp Krausewitz, Markus Essler, Thomas Büttner, Jim Küppers et al.

Apr 30, 2026

Journal of Nuclear Medicine

Prostate Cancer Treatment and Research

article

Quantifying the Renal Impact of [ ¹⁷⁷ Lu]Lu-PSMA-617: A Longitudinal Analysis of Real-World Data from the LUMEN Registry

Philipp Krausewitz, Markus Essler, Thomas Büttner, Jim Küppers, Milka Marinova, Barbara Kreppel, Leander Fritzsche, Christian Hoffmann, Florian Gärtner, Manuel Ritter

April 30, 2026article en

Abstract

Lu]Lu-PSMA-617 is associated with a slight long-term average decline in eGFR. Although this is unlikely to be clinically relevant for late-stage mCRPC, the cumulative dose effect warrants careful monitoring in earlier disease stages.

Journal of Nuclear Medicine

University Hospital Bonn (DE)

Openalex Percentile: Top 11%

Prostate Cancer Treatment and Research

DOI Source OpenAlex

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